Web Application connect to Application server

Hello, 

I have met an issue today: I can't create any user from the web portal anymore. I have an error like: 

An exception has occurred while executing the form method Popup0_Popup0_ControlRef2_Container6_Button1_Method.
Application server returned an error.
An error occurred.
So I went to check in the application server and all thing seems good.
But in the web server when I tried to check the connection to my application server (by adding a new connection from the WebDesigner.ConfigFileEditor) I got another issue:
The requested operation cannot be completed. The computer must be trusted for delegation and the current user account must be configured to allow delegation.
Ps: my application server is connected to my DB through a SQL cluster. but the cluster works well.

Did anybody already meet this issue?

Thanks all, for your answers,

Regards,
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